Mesotherapy is a technique that uses injections of vitamins,minerals, enzymes and plant extracts to rejuvenate and tighten skin. - fade wrinkles and lines - tighten loose skin - recontour - lighten pigmented skin - treat alopecia, a condition that causes hair loss The technique uses very fine needles to deliver a series of injections into the middle layer (mesoderm) of skin. The idea behind mesotherapy is that it corrects underlying issues like poor circulation and inflammation that cause skin damage.